The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IBSP-20-RE | 20 (40 μL) | 200 μL |  |
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| IBSP-20-OR | 20 (40 μL) | 200 μL |  |
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| IBSP-20-GO | 20 (40 μL) | 200 μL |  |
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| IBSP-20-GR | 20 (40 μL) | 200 μL |  |
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| IBSP-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008]
Gene Symbol : IBSP
Gene Name : Integrin binding sialoprotein
Chromosome : CHR 4: 877,995,49-878,124,48
Locus : 4q22.1
Alt. Genes : YAF2
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