The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ICAM3-20-RE | 20 (40 μL) | 200 μL |  |
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| ICAM3-20-OR | 20 (40 μL) | 200 μL |  |
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| ICAM3-20-GO | 20 (40 μL) | 200 μL |  |
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| ICAM3-20-GR | 20 (40 μL) | 200 μL |  |
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| ICAM3-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
Gene Symbol : ICAM3
Gene Name : Intercellular adhesion molecule 3
Chromosome : CHR 19: 103,398,33-103,337,75
Locus : 19p13.2
Alt. Genes : SLC25A13
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