This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ICAM4-20-RE | 20 (40 μL) | 200 μL |  |
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| ICAM4-20-OR | 20 (40 μL) | 200 μL |  |
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| ICAM4-20-GO | 20 (40 μL) | 200 μL |  |
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| ICAM4-20-GR | 20 (40 μL) | 200 μL |  |
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| ICAM4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Symbol : ICAM4
Gene Name : Intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
Chromosome : CHR 19: 102,869,66-102,885,83
Locus : 19p13.2
Alt. Genes : FARP1
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