IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IDI1-20-RE | 20 (40 μL) | 200 μL |  |
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| IDI1-20-OR | 20 (40 μL) | 200 μL |  |
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| IDI1-20-GO | 20 (40 μL) | 200 μL |  |
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| IDI1-20-GR | 20 (40 μL) | 200 μL |  |
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| IDI1-20-AQ | 20 (40 μL) | 200 μL |  |
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IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq, Jul 2008]
Gene Symbol : IDI1
Gene Name : Isopentenyl-diphosphate delta isomerase 1
Chromosome : CHR 10: 105,671,5-103,941,8
Locus : 10p15.3
Alt. Genes : LHFPL6
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