The protein encoded by this gene catalyzes the conversion of isopentenyl diphosphate to dimethylallyl diphosphate, which is a precursor for the synthesis of cholesterol and other isoprenoids. This gene, which is a product of an ancestral gene duplication event, encodes a protein that may be involved in the aggregation of alpha-synuclein in the cerebral cortex of patients with Lewy body disease. In addition, segmental copy number gains in this locus have been associated with sporadic amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IDI2-20-RE | 20 (40 μL) | 200 μL |  |
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| IDI2-20-OR | 20 (40 μL) | 200 μL |  |
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| IDI2-20-GO | 20 (40 μL) | 200 μL |  |
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| IDI2-20-GR | 20 (40 μL) | 200 μL |  |
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| IDI2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene catalyzes the conversion of isopentenyl diphosphate to dimethylallyl diphosphate, which is a precursor for the synthesis of cholesterol and other isoprenoids. This gene, which is a product of an ancestral gene duplication event, encodes a protein that may be involved in the aggregation of alpha-synuclein in the cerebral cortex of patients with Lewy body disease. In addition, segmental copy number gains in this locus have been associated with sporadic amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2016]
Gene Symbol : IDI2
Gene Name : Isopentenyl-diphosphate delta isomerase 2
Chromosome : CHR 10: 102,585,8-101,890,6
Locus : 10p15.3
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