This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IFI16-20-RE | 20 (40 μL) | 200 μL |  |
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| IFI16-20-OR | 20 (40 μL) | 200 μL |  |
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| IFI16-20-GO | 20 (40 μL) | 200 μL |  |
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| IFI16-20-GR | 20 (40 μL) | 200 μL |  |
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| IFI16-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]
Gene Symbol : IFI16
Gene Name : Interferon gamma inducible protein 16
Chromosome : CHR 1: 158,999,967-159,055,154
Locus : 1q23.1
Alt. Genes : MAB21L2
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