This gene encodes a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195). [provided by RefSeq, Aug 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IFITM5-20-RE | 20 (40 μL) | 200 μL |  |
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| IFITM5-20-OR | 20 (40 μL) | 200 μL |  |
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| IFITM5-20-GO | 20 (40 μL) | 200 μL |  |
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| IFITM5-20-GR | 20 (40 μL) | 200 μL |  |
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| IFITM5-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195). [provided by RefSeq, Aug 2012]
Gene Symbol : IFITM5
Gene Name : Interferon induced transmembrane protein 5
Chromosome : CHR 11: 299,525-298,199
Locus : 11p15.5
Alt. Genes : OPTN
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