This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IGFBP3-20-RE | 20 (40 μL) | 200 μL |  |
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| IGFBP3-20-OR | 20 (40 μL) | 200 μL |  |
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| IGFBP3-20-GO | 20 (40 μL) | 200 μL |  |
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| IGFBP3-20-GR | 20 (40 μL) | 200 μL |  |
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| IGFBP3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : IGFBP3
Gene Name : Insulin like growth factor binding protein 3
Chromosome : CHR 7: 459,212,71-459,122,44
Locus : 7p12.3
Alt. Genes : RBM12
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