The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
IL11-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
IL11-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
IL11-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
IL11-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
IL11-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Gene Symbol : IL11
Gene Name : Interleukin 11
Chromosome : CHR 19: 553,704,62-553,643,81
Locus : 19q13.42
Alt. Genes : PDZK1IP1
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