The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL18R1-20-RE | 20 (40 μL) | 200 μL |  |
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| IL18R1-20-OR | 20 (40 μL) | 200 μL |  |
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| IL18R1-20-GO | 20 (40 μL) | 200 μL |  |
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| IL18R1-20-GR | 20 (40 μL) | 200 μL |  |
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| IL18R1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Gene Symbol : IL18R1
Gene Name : Interleukin 18 receptor 1
Chromosome : CHR 2: 102,355,816-102,398,776
Locus : 2q12.1
Alt. Genes : TRIM28
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