The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL18RAP-20-RE | 20 (40 μL) | 200 μL |  |
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| IL18RAP-20-OR | 20 (40 μL) | 200 μL |  |
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| IL18RAP-20-GO | 20 (40 μL) | 200 μL |  |
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| IL18RAP-20-GR | 20 (40 μL) | 200 μL |  |
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| IL18RAP-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
Gene Symbol : IL18RAP
Gene Name : Interleukin 18 receptor accessory protein
Chromosome : CHR 2: 102,418,550-102,452,567
Locus : 2q12.1
Alt. Genes : AKAP9
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