The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL1A-20-RE | 20 (40 μL) | 200 μL |  |
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| IL1A-20-OR | 20 (40 μL) | 200 μL |  |
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| IL1A-20-GO | 20 (40 μL) | 200 μL |  |
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| IL1A-20-GR | 20 (40 μL) | 200 μL |  |
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| IL1A-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
Gene Symbol : IL1A
Gene Name : Interleukin 1 alpha
Chromosome : CHR 2: 112,785,397-112,773,914
Locus : 2q14.1
Alt. Genes : SERF2
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