Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Nov 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL1RAP-20-RE | 20 (40 μL) | 200 μL |  |
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| IL1RAP-20-OR | 20 (40 μL) | 200 μL |  |
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| IL1RAP-20-GO | 20 (40 μL) | 200 μL |  |
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| IL1RAP-20-GR | 20 (40 μL) | 200 μL |  |
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| IL1RAP-20-AQ | 20 (40 μL) | 200 μL |  |
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Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Nov 2009]
Gene Symbol : IL1RAP
Gene Name : Interleukin 1 receptor accessory protein
Chromosome : CHR 3: 190,514,050-190,657,196
Locus : 3q28
Alt. Genes : FEM1B
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