The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signalling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization. [provided by RefSeq, Jul 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL1RAPL1-20-RE | 20 (40 μL) | 200 μL |  |
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| IL1RAPL1-20-OR | 20 (40 μL) | 200 μL |  |
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| IL1RAPL1-20-GO | 20 (40 μL) | 200 μL |  |
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| IL1RAPL1-20-GR | 20 (40 μL) | 200 μL |  |
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| IL1RAPL1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signalling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization. [provided by RefSeq, Jul 2017]
Gene Symbol : IL1RAPL1
Gene Name : Interleukin 1 receptor accessory protein like 1
Chromosome : CHR X: 285,875,63-299,563,49
Locus : Xp21.3-p21.2
Alt. Genes : TRAP1
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