The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL2-20-RE | 20 (40 μL) | 200 μL |  |
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| IL2-20-OR | 20 (40 μL) | 200 μL |  |
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| IL2-20-GO | 20 (40 μL) | 200 μL |  |
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| IL2-20-GR | 20 (40 μL) | 200 μL |  |
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| IL2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
Gene Symbol : IL2
Gene Name : Interleukin 2
Chromosome : CHR 4: 122,456,494-122,449,478
Locus : 4q27
Alt. Genes : CFM1
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