This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL21-20-RE | 20 (40 μL) | 200 μL |  |
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| IL21-20-OR | 20 (40 μL) | 200 μL |  |
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| IL21-20-GO | 20 (40 μL) | 200 μL |  |
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| IL21-20-GR | 20 (40 μL) | 200 μL |  |
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| IL21-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Symbol : IL21
Gene Name : Interleukin 21
Chromosome : CHR 4: 122,621,056-122,612,627
Locus : 4q27
Alt. Genes : LINC01587
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