The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL27-20-RE | 20 (40 μL) | 200 μL |  |
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| IL27-20-OR | 20 (40 μL) | 200 μL |  |
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| IL27-20-GO | 20 (40 μL) | 200 μL |  |
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| IL27-20-GR | 20 (40 μL) | 200 μL |  |
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| IL27-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008]
Gene Symbol : IL27
Gene Name : Interleukin 27
Chromosome : CHR 16: 285,267,29-284,993,61
Locus : 16p12.1-p11.2
Alt. Genes : ATP6AP2
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