In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL27RA-20-RE | 20 (40 μL) | 200 μL |  |
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| IL27RA-20-OR | 20 (40 μL) | 200 μL |  |
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| IL27RA-20-GO | 20 (40 μL) | 200 μL |  |
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| IL27RA-20-GR | 20 (40 μL) | 200 μL |  |
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| IL27RA-20-AQ | 20 (40 μL) | 200 μL |  |
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In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq, Jul 2008]
Gene Symbol : IL27RA
Gene Name : Interleukin 27 receptor subunit alpha
Chromosome : CHR 19: 140,317,39-140,529,18
Locus : 19p13.12
Alt. Genes : SLC25A13
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