IL5RA FISH Probe

The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
IL5RA-20-RE 20 (40 μL) 200 μL color Request Pricing
IL5RA-20-OR 20 (40 μL) 200 μL color Request Pricing
IL5RA-20-GO 20 (40 μL) 200 μL color Request Pricing
IL5RA-20-GR 20 (40 μL) 200 μL color Request Pricing
IL5RA-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011]

Gene Details

Gene Symbol : IL5RA

Gene Name : Interleukin 5 receptor subunit alpha

Chromosome : CHR 3: 311,041,3-306,632,3

Locus : 3p26.2

Alt. Genes : AKAP9

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