The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IMPDH1-20-RE | 20 (40 μL) | 200 μL |  |
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| IMPDH1-20-OR | 20 (40 μL) | 200 μL |  |
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| IMPDH1-20-GO | 20 (40 μL) | 200 μL |  |
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| IMPDH1-20-GR | 20 (40 μL) | 200 μL |  |
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| IMPDH1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Symbol : IMPDH1
Gene Name : Inosine monophosphate dehydrogenase 1
Chromosome : CHR 7: 128,409,987-128,392,276
Locus : 7q32.1
Alt. Genes : ABI2
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