This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Jan 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IQCB1-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| IQCB1-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| IQCB1-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| IQCB1-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| IQCB1-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Jan 2016]
Gene Symbol : IQCB1
Gene Name : IQ motif containing B1
Chromosome : CHR 3: 121,835,078-121,769,760
Locus : 3q21.1
Alt. Genes : CELA3A
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.