This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IRAK3-20-RE | 20 (40 μL) | 200 μL |  |
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| IRAK3-20-OR | 20 (40 μL) | 200 μL |  |
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| IRAK3-20-GO | 20 (40 μL) | 200 μL |  |
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| IRAK3-20-GR | 20 (40 μL) | 200 μL |  |
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| IRAK3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Symbol : IRAK3
Gene Name : Interleukin 1 receptor associated kinase 3
Chromosome : CHR 12: 661,891,97-662,546,21
Locus : 12q14.3
Alt. Genes : ABI2
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