This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Dec 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IRF5-20-RE | 20 (40 μL) | 200 μL |  |
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| IRF5-20-OR | 20 (40 μL) | 200 μL |  |
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| IRF5-20-GO | 20 (40 μL) | 200 μL |  |
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| IRF5-20-GR | 20 (40 μL) | 200 μL |  |
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| IRF5-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Dec 2016]
Gene Symbol : IRF5
Gene Name : Interferon regulatory factor 5
Chromosome : CHR 7: 128,937,736-128,950,041
Locus : 7q32.1
Alt. Genes : ZNF263
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