Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
IRF8-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
IRF8-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
IRF8-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
IRF8-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
IRF8-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq, Jul 2008]
Gene Symbol : IRF8
Gene Name : Interferon regulatory factor 8
Chromosome : CHR 16: 858,991,67-859,226,05
Locus : 16q24.1
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