This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IRGM-20-RE | 20 (40 μL) | 200 μL |  |
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| IRGM-20-OR | 20 (40 μL) | 200 μL |  |
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| IRGM-20-GO | 20 (40 μL) | 200 μL |  |
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| IRGM-20-GR | 20 (40 μL) | 200 μL |  |
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| IRGM-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016]
Gene Symbol : IRGM
Gene Name : Immunity related GTPase M
Chromosome : CHR 5: 150,846,522-150,902,401
Locus : 5q33.1
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