This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IRS2-20-RE | 20 (40 μL) | 200 μL |  |
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| IRS2-20-OR | 20 (40 μL) | 200 μL |  |
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| IRS2-20-GO | 20 (40 μL) | 200 μL |  |
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| IRS2-20-GR | 20 (40 μL) | 200 μL |  |
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| IRS2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008]
Gene Symbol : IRS2
Gene Name : Insulin receptor substrate 2
Chromosome : CHR 13: 109,786,566-109,753,836
Locus : 13q34
Alt. Genes : RASA4
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