This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ISL1-20-RE | 20 (40 μL) | 200 μL |  |
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| ISL1-20-OR | 20 (40 μL) | 200 μL |  |
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| ISL1-20-GO | 20 (40 μL) | 200 μL |  |
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| ISL1-20-GR | 20 (40 μL) | 200 μL |  |
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| ISL1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]
Gene Symbol : ISL1
Gene Name : ISL LIM homeobox 1
Chromosome : CHR 5: 513,831,23-513,947,29
Locus : 5q11.1
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