This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ITGA2-20-RE | 20 (40 μL) | 200 μL |  |
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| ITGA2-20-OR | 20 (40 μL) | 200 μL |  |
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| ITGA2-20-GO | 20 (40 μL) | 200 μL |  |
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| ITGA2-20-GR | 20 (40 μL) | 200 μL |  |
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| ITGA2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Symbol : ITGA2
Gene Name : Integrin subunit alpha 2
Chromosome : CHR 5: 529,893,25-530,947,78
Locus : 5q11.2
Alt. Genes : LRPPRC
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