The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ITGA3-20-RE | 20 (40 μL) | 200 μL |  |
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| ITGA3-20-OR | 20 (40 μL) | 200 μL |  |
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| ITGA3-20-GO | 20 (40 μL) | 200 μL |  |
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| ITGA3-20-GR | 20 (40 μL) | 200 μL |  |
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| ITGA3-20-AQ | 20 (40 μL) | 200 μL |  |
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The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015]
Gene Symbol : ITGA3
Gene Name : Integrin subunit alpha 3
Chromosome : CHR 17: 500,559,67-500,904,84
Locus : 17q21.33
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