The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ITGA5-20-RE | 20 (40 μL) | 200 μL |  |
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| ITGA5-20-OR | 20 (40 μL) | 200 μL |  |
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| ITGA5-20-GO | 20 (40 μL) | 200 μL |  |
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| ITGA5-20-GR | 20 (40 μL) | 200 μL |  |
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| ITGA5-20-AQ | 20 (40 μL) | 200 μL |  |
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The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
Gene Symbol : ITGA5
Gene Name : Integrin subunit alpha 5
Chromosome : CHR 12: 544,192,65-543,952,60
Locus : 12q13.13
Alt. Genes : PLXNC1
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