This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ITGAX-20-RE | 20 (40 μL) | 200 μL |  |
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| ITGAX-20-OR | 20 (40 μL) | 200 μL |  |
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| ITGAX-20-GO | 20 (40 μL) | 200 μL |  |
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| ITGAX-20-GR | 20 (40 μL) | 200 μL |  |
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| ITGAX-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Gene Symbol : ITGAX
Gene Name : Integrin subunit alpha X
Chromosome : CHR 16: 313,551,33-313,829,96
Locus : 16p11.2
Alt. Genes : LPCAT3
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