This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ITGB8-20-RE | 20 (40 μL) | 200 μL |  |
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| ITGB8-20-OR | 20 (40 μL) | 200 μL |  |
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| ITGB8-20-GO | 20 (40 μL) | 200 μL |  |
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| ITGB8-20-GR | 20 (40 μL) | 200 μL |  |
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| ITGB8-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : ITGB8
Gene Name : Integrin subunit beta 8
Chromosome : CHR 7: 203,298,18-204,157,58
Locus : 7p21.1
Alt. Genes : HIPK3
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