This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| JARID2-20-RE | 20 (40 μL) | 200 μL |  |
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| JARID2-20-OR | 20 (40 μL) | 200 μL |  |
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| JARID2-20-GO | 20 (40 μL) | 200 μL |  |
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| JARID2-20-GR | 20 (40 μL) | 200 μL |  |
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| JARID2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]
Gene Symbol : JARID2
Gene Name : Jumonji and AT-rich interaction domain containing 2
Chromosome : CHR 6: 152,459,74-155,220,41
Locus : 6p22.3
Alt. Genes : FEM1B
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