This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KCNIP3-20-RE | 20 (40 μL) | 200 μL |  |
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| KCNIP3-20-OR | 20 (40 μL) | 200 μL |  |
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| KCNIP3-20-GO | 20 (40 μL) | 200 μL |  |
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| KCNIP3-20-GR | 20 (40 μL) | 200 μL |  |
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| KCNIP3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Symbol : KCNIP3
Gene Name : Potassium voltage-gated channel interacting protein 3
Chromosome : CHR 2: 952,973,23-953,860,76
Locus : 2q11.1
Alt. Genes : TRAP1
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