KCNN2 FISH Probe

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
KCNN2-20-RE 20 (40 μL) 200 μL color Request Pricing
KCNN2-20-OR 20 (40 μL) 200 μL color Request Pricing
KCNN2-20-GO 20 (40 μL) 200 μL color Request Pricing
KCNN2-20-GR 20 (40 μL) 200 μL color Request Pricing
KCNN2-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Gene Details

Gene Symbol : KCNN2

Gene Name : Potassium calcium-activated channel subfamily N member 2

Chromosome : CHR 5: 114,056,005-114,496,499

Locus : 5q22.3

Alt. Genes : OPTN

Request Pricing

Lorem Ipsum is simply dummy text of the printing and typesetting industry.

Lorem Ipsum is simply dummy text of the printing and typesetting industry.