The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KCNQ2-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| KCNQ2-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| KCNQ2-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| KCNQ2-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| KCNQ2-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : KCNQ2
Gene Name : Potassium voltage-gated channel subfamily Q member 2
Chromosome : CHR 20: 634,726,76-634,002,07
Locus : 20q13.33
Alt. Genes : LINC01587
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.