This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
KDM5B-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
KDM5B-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
KDM5B-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
KDM5B-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
KDM5B-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Gene Symbol : KDM5B
Gene Name : Lysine demethylase 5B
Chromosome : CHR 1: 202,809,469-202,725,184
Locus : 1q32.1
Alt. Genes : RBM12
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