This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KEAP1-20-RE | 20 (40 μL) | 200 μL |  |
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| KEAP1-20-OR | 20 (40 μL) | 200 μL |  |
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| KEAP1-20-GO | 20 (40 μL) | 200 μL |  |
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| KEAP1-20-GR | 20 (40 μL) | 200 μL |  |
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| KEAP1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : KEAP1
Gene Name : Kelch like ECH associated protein 1
Chromosome : CHR 19: 105,033,77-104,861,19
Locus : 19p13.2
Alt. Genes : FEM1B
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