The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KIRREL3-20-RE | 20 (40 μL) | 200 μL |  |
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| KIRREL3-20-OR | 20 (40 μL) | 200 μL |  |
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| KIRREL3-20-GO | 20 (40 μL) | 200 μL |  |
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| KIRREL3-20-GR | 20 (40 μL) | 200 μL |  |
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| KIRREL3-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
Gene Symbol : KIRREL3
Gene Name : Kirre like nephrin family adhesion molecule 3
Chromosome : CHR 11: 127,003,459-126,423,492
Locus : 11q24.2
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