This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KIT-20-RE | 20 (40 μL) | 200 μL |  |
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| KIT-20-OR | 20 (40 μL) | 200 μL |  |
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| KIT-20-GO | 20 (40 μL) | 200 μL |  |
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| KIT-20-GR | 20 (40 μL) | 200 μL |  |
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| KIT-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : KIT
Gene Name : KIT proto-oncogene receptor tyrosine kinase
Chromosome : CHR 4: 546,579,27-547,407,14
Locus : 4q12
Alt. Genes : DNAL4
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