This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KLF1-20-RE | 20 (40 μL) | 200 μL |  |
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| KLF1-20-OR | 20 (40 μL) | 200 μL |  |
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| KLF1-20-GO | 20 (40 μL) | 200 μL |  |
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| KLF1-20-GR | 20 (40 μL) | 200 μL |  |
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| KLF1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009]
Gene Symbol : KLF1
Gene Name : Kruppel like factor 1
Chromosome : CHR 19: 128,872,02-128,844,21
Locus : 19p13.13
Alt. Genes : AASS
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