Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KLF12-20-RE | 20 (40 μL) | 200 μL |  |
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| KLF12-20-OR | 20 (40 μL) | 200 μL |  |
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| KLF12-20-GO | 20 (40 μL) | 200 μL |  |
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| KLF12-20-GR | 20 (40 μL) | 200 μL |  |
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| KLF12-20-AQ | 20 (40 μL) | 200 μL |  |
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Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : KLF12
Gene Name : Kruppel like factor 12
Chromosome : CHR 13: 741,682,94-736,860,11
Locus : 13q22.1
Alt. Genes : FEM1B
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