This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KLF4-20-RE | 20 (40 μL) | 200 μL |  |
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| KLF4-20-OR | 20 (40 μL) | 200 μL |  |
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| KLF4-20-GO | 20 (40 μL) | 200 μL |  |
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| KLF4-20-GR | 20 (40 μL) | 200 μL |  |
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| KLF4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
Gene Symbol : KLF4
Gene Name : Kruppel like factor 4
Chromosome : CHR 9: 107,489,719-107,484,851
Locus : 9q31.2
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