This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KLF8-20-RE | 20 (40 μL) | 200 μL |  |
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| KLF8-20-OR | 20 (40 μL) | 200 μL |  |
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| KLF8-20-GO | 20 (40 μL) | 200 μL |  |
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| KLF8-20-GR | 20 (40 μL) | 200 μL |  |
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| KLF8-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Gene Symbol : KLF8
Gene Name : Kruppel like factor 8
Chromosome : CHR X: 559,081,22-562,915,30
Locus : Xp11.21
Alt. Genes : AASS
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