This gene encodes a member of the kelch-like (KLHL) family of proteins, which is involved in B-lymphocyte antigen receptor signaling and germinal-center B-cell maturation. The encoded protein contains an N-terminal broad-complex, tramtrack and bric a brac (BTB) domain that facilitates protein binding and dimerization, a BTB and C-terminal kelch (BACK) domain, and six C-terminal kelch repeat domains. Naturally occurring mutations in this gene are associated with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KLHL6-20-RE | 20 (40 μL) | 200 μL |  |
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| KLHL6-20-OR | 20 (40 μL) | 200 μL |  |
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| KLHL6-20-GO | 20 (40 μL) | 200 μL |  |
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| KLHL6-20-GR | 20 (40 μL) | 200 μL |  |
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| KLHL6-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the kelch-like (KLHL) family of proteins, which is involved in B-lymphocyte antigen receptor signaling and germinal-center B-cell maturation. The encoded protein contains an N-terminal broad-complex, tramtrack and bric a brac (BTB) domain that facilitates protein binding and dimerization, a BTB and C-terminal kelch (BACK) domain, and six C-terminal kelch repeat domains. Naturally occurring mutations in this gene are associated with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
Gene Symbol : KLHL6
Gene Name : Kelch like family member 6
Chromosome : CHR 3: 183,555,711-183,487,530
Locus : 3q27.1
Alt. Genes : PREB
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