This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KMT2B-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| KMT2B-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| KMT2B-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| KMT2B-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| KMT2B-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]
Gene Symbol : KMT2B
Gene Name : Lysine methyltransferase 2B
Chromosome : CHR 19: 357,178,17-357,388,79
Locus : 19q13.12
Alt. Genes : OPTN
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.