The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KPNA4-20-RE | 20 (40 μL) | 200 μL |  |
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| KPNA4-20-OR | 20 (40 μL) | 200 μL |  |
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| KPNA4-20-GO | 20 (40 μL) | 200 μL |  |
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| KPNA4-20-GR | 20 (40 μL) | 200 μL |  |
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| KPNA4-20-AQ | 20 (40 μL) | 200 μL |  |
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The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq, Jul 2008]
Gene Symbol : KPNA4
Gene Name : Karyopherin subunit alpha 4
Chromosome : CHR 3: 160,565,587-160,494,994
Locus : 3q25.33
Alt. Genes : KIF20A
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