This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KRAS-20-RE | 20 (40 μL) | 200 μL |  |
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| KRAS-20-OR | 20 (40 μL) | 200 μL |  |
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| KRAS-20-GO | 20 (40 μL) | 200 μL |  |
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| KRAS-20-GR | 20 (40 μL) | 200 μL |  |
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| KRAS-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
Gene Symbol : KRAS
Gene Name : KRAS proto-oncogene, GTPase
Chromosome : CHR 12: 252,520,92-252,047,88
Locus : 12p12.1
Alt. Genes : RBM12
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