This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KREMEN1-20-RE | 20 (40 μL) | 200 μL |  |
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| KREMEN1-20-OR | 20 (40 μL) | 200 μL |  |
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| KREMEN1-20-GO | 20 (40 μL) | 200 μL |  |
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| KREMEN1-20-GR | 20 (40 μL) | 200 μL |  |
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| KREMEN1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : KREMEN1
Gene Name : Kringle containing transmembrane protein 1
Chromosome : CHR 22: 290,730,77-291,683,32
Locus : 22q12.1
Alt. Genes : LRPPRC
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