This gene encodes an oxidoreductase that promotes fatty-acid oxidation, with concomitant inflammasome activation, mitochondrial and NADPH-oxidase-dependent reactive oxygen species production, and bactericidal activity of macrophages. The encoded protein forms a complex with fatty acid synthase on peroxisomes and is thought to be modulated by peroxisome proliferator-activated receptor signaling events. Naturally occurring mutations in this gene are associated with inflammatory bowel disease, Behcet's disease, leprosy, ulcerative colitis, early-onset Crohn's disease, and systemic juvenile idiopathic arthritis. [provided by RefSeq, Apr 2017]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
LACC1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
LACC1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
LACC1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
LACC1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
LACC1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes an oxidoreductase that promotes fatty-acid oxidation, with concomitant inflammasome activation, mitochondrial and NADPH-oxidase-dependent reactive oxygen species production, and bactericidal activity of macrophages. The encoded protein forms a complex with fatty acid synthase on peroxisomes and is thought to be modulated by peroxisome proliferator-activated receptor signaling events. Naturally occurring mutations in this gene are associated with inflammatory bowel disease, Behcet's disease, leprosy, ulcerative colitis, early-onset Crohn's disease, and systemic juvenile idiopathic arthritis. [provided by RefSeq, Apr 2017]
Gene Symbol : LACC1
Gene Name : Laccase domain containing 1
Chromosome : CHR 13: 438,788,33-438,939,31
Locus : 13q14.11
Alt. Genes : PREB
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.