LACC1 FISH Probe

This gene encodes an oxidoreductase that promotes fatty-acid oxidation, with concomitant inflammasome activation, mitochondrial and NADPH-oxidase-dependent reactive oxygen species production, and bactericidal activity of macrophages. The encoded protein forms a complex with fatty acid synthase on peroxisomes and is thought to be modulated by peroxisome proliferator-activated receptor signaling events. Naturally occurring mutations in this gene are associated with inflammatory bowel disease, Behcet's disease, leprosy, ulcerative colitis, early-onset Crohn's disease, and systemic juvenile idiopathic arthritis. [provided by RefSeq, Apr 2017]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
LACC1-20-RE 20 (40 μL) 200 μL color Request Pricing
LACC1-20-OR 20 (40 μL) 200 μL color Request Pricing
LACC1-20-GO 20 (40 μL) 200 μL color Request Pricing
LACC1-20-GR 20 (40 μL) 200 μL color Request Pricing
LACC1-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes an oxidoreductase that promotes fatty-acid oxidation, with concomitant inflammasome activation, mitochondrial and NADPH-oxidase-dependent reactive oxygen species production, and bactericidal activity of macrophages. The encoded protein forms a complex with fatty acid synthase on peroxisomes and is thought to be modulated by peroxisome proliferator-activated receptor signaling events. Naturally occurring mutations in this gene are associated with inflammatory bowel disease, Behcet's disease, leprosy, ulcerative colitis, early-onset Crohn's disease, and systemic juvenile idiopathic arthritis. [provided by RefSeq, Apr 2017]

Gene Details

Gene Symbol : LACC1

Gene Name : Laccase domain containing 1

Chromosome : CHR 13: 438,788,33-438,939,31

Locus : 13q14.11

Alt. Genes : PREB

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